Overview

Intrauterine insemination (IUI) — a type of artificial insemination — is a procedure for treating infertility.

Sperm that have been washed and concentrated are placed directly in your uterus around the time your ovary releases one or more eggs to be fertilized. Older types of artificial insemination placed the sperm in the vagina. While this was easier, it was not as successful as the current procedure.

The hoped-for outcome of intrauterine insemination is for the sperm to swim into the fallopian tube and fertilize a waiting egg, resulting in a normal pregnancy. Depending on the reasons for infertility, IUI can be coordinated with your normal cycle or with fertility medications.

June 21, 2016
References
  1. Treating infertility. American College of Obstetricians and Gynecologists. http://www.acog.org/Patients/FAQs/Treating-Infertility. Accessed April 7, 2016.
  2. Infertility FAQs. Centers for Disease Control and Prevention. http://www.cdc.gov/reproductivehealth/Infertility/. Accessed April 7, 2016.
  3. Infertility fact sheet. Womenshealth.gov. http://www.womenshealth.gov/publications/our-publications/fact-sheet/infertility.html. Accessed April 8, 2016.
  4. Ginsburg ES. Procedure for intrauterine insemination (IUI) using processed sperm. http://www.uptodate.com/home. Accessed April 8, 2016.
  5. Intrauterine insemination (IUI). ReproductiveFacts.org. http://www.reproductivefacts.org/awards/detail.aspx?id=8576 Accessed April 18, 2016.
  6. Luco SM, et al. The evaluation of pre and post processing semen analysis parameters at the time of intrauterine insemination in couples diagnosed with male factor infertility and pregnancy rates based on stimulation agent. A retrospective cohort study. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2014;179:159.
  7. Hornstein MD, et al. Unexplained infertility. http://www.uptodate.com/home. Accessed April 18, 2016.
  8. Coddington III CC (expert opinion). Mayo Clinic, Rochester, Minn. April 18, 2016.