There are several potential treatment options for brain AVM. The main goal of treatment is to prevent hemorrhage, but treatment to control seizures or other neurological complications also may be considered.
Your doctor will determine the most appropriate treatment for your condition, depending on your age, health, and the size and location of the abnormal blood vessels.
Medications also may be used to treat symptoms caused by the AVM, such as headaches or seizures.
Surgery is the most common treatment for brain AVMs. There are three different surgical options for treating AVMs:
Surgical removal (resection). If the brain AVM has bled or is in an area that can easily be reached, surgical removal of the AVM via conventional brain surgery may be recommended. In this procedure, your neurosurgeon removes part of your skull temporarily to gain access to the AVM.
With the help of a high-powered microscope, the surgeon seals off the AVM with special clips and carefully removes it from surrounding brain tissue. The surgeon then reattaches the skull bone and closes the incision in your scalp.
Resection is usually done when the AVM can be removed with little risk of hemorrhage or seizures. AVMs that are in deep brain regions carry a higher risk of complications. In these cases, your doctor may recommend other treatments.
Endovascular embolization. In this procedure, your doctor inserts a long, thin tube (catheter) into a leg artery and threads it through blood vessels to your brain using X-ray imaging.
The catheter is positioned in one of the feeding arteries to the AVM, and injects an embolizing agent, such as small particles, a glue-like substance, microcoils or other materials, to block the artery and reduce blood flow into the AVM.
Endovascular embolization is less invasive than traditional surgery. It may be performed alone, but is frequently used prior to other surgical treatments to make the procedure safer by reducing the size of the AVM or the likelihood of bleeding.
In some large brain AVMs, endovascular embolization may be used to reduce stroke-like symptoms by redirecting blood back to normal brain tissue.
Stereotactic radiosurgery (SRS). This treatment uses precisely focused radiation to destroy the AVM. It is not surgery in the literal sense because there is no incision.
Instead, SRS directs many highly targeted radiation beams at the AVM to damage the blood vessels and cause scarring. The scarred AVM blood vessels then slowly clot off in one to three years following treatment.
This treatment is most appropriate for small AVMs that are difficult to remove with conventional surgery and for those that haven't caused a life-threatening hemorrhage.
If you have few or no symptoms or if your AVM is in an area of your brain that's hard to treat, your doctor may prefer to monitor your condition with regular checkups.
Potential future treatments
Researchers are currently studying ways to better predict the risk of hemorrhage in people with brain AVM to better guide treatment decisions. For example, high blood pressure within the AVM and hereditary syndromes associated with neurological issues may play a role.
Innovations in imaging technology, such as 3-D imaging, functional imaging and brain tract mapping also are being evaluated and have the potential to improve surgical precision and safety in removing brain AVMs and preserving surrounding vessels.
In addition, ongoing advances in embolization, radiosurgery and microsurgery techniques are making previously inoperable brain AVMs more accessible and safer for surgical removal.
June 29, 2016
- Arteriovenous malformations and other vascular lesions of the central nervous system fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/avms/detail_avms.htm. Accessed Jan. 6, 2015.
- What is an arteriovenous malformation? American Stroke Association. http://www.strokeassociation.org/STROKEORG/AboutStroke/TypesofStroke/HemorrhagicBleeds/What-Is-an-Arteriovenous-Malformation-AVM_UCM_310099_Article.jsp. Accessed Jan. 6, 2015.
- Singer RJ. Brain arteriovenous malformations. http://www.uptodate.com/home. Accessed Jan. 6, 2015.
- Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Jan. 6, 2015.
- Van Beijnum J, et al. Treatment of brain arteriovenous malformations: A systemic review and meta-analysis. Journal of the American Medical Association. 2011;306:2011.
- Meyers P, et al. Indications for the performance of intracranial endovascular neurointerventional procedures. Circulation. 2009;119:2235.
- Bendok B, et al. Advances and innovations in brain arteriovenous malformation surgery. Neurosurgery. 2014;74(suppl):S60.
- Let's talk about emotional changes after stroke. American Stroke Association. http://www.strokeassociation.org/idc/groups/stroke-public/@wcm/@hcm/documents/downloadable/ucm_309718.pdf. Accessed Jan. 9, 2015.
- Bendok BR (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. Feb. 5, 2015.
- Rice EM. Decision Support System. Mayo Clinic. Rochester, Minn. Jan. 20, 2015.
Brain AVM (arteriovenous malformation)