Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of immune globulin and recombinant human hyaluronidase injection in the children younger than 2 years of age. Safety has not been established.

Geriatric

Appropriate studies on the relationship of age to the effects of immune globulin and recombinant human hyaluronidase injection have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of immune globulin and recombinant human hyaluronidase injection in the elderly. However, elderly patients are more likely to have age-related blood clotting problems, kidney or heart problems, which may require caution for patients receiving immune globulin and recombinant human hyaluronidase injection.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Adenovirus Vaccine, Live
  • Bacillus of Calmette and Guerin Vaccine, Live
  • Benzocaine
  • Bupivacaine
  • Bupivacaine Liposome
  • Butacaine
  • Chloroprocaine
  • Cholera Vaccine, Live
  • Cocaine
  • Dengue Tetravalent Vaccine, Live
  • Dibucaine
  • Ebola Zaire Vaccine, Live
  • Etidocaine
  • Influenza Virus Vaccine, Live
  • Lidocaine
  • Measles Virus Vaccine, Live
  • Mepivacaine
  • Mumps Virus Vaccine, Live
  • Poliovirus Vaccine, Live
  • Prilocaine
  • Procaine
  • Proparacaine
  • Propoxycaine
  • Ravulizumab-cwvz
  • Ropivacaine
  • Rotavirus Vaccine, Live
  • Rubella Virus Vaccine, Live
  • Smallpox Monkeypox Vaccine, Live Non-Replicating
  • Smallpox Vaccine
  • Tetracaine
  • Typhoid Vaccine, Live
  • Varicella Virus Vaccine, Live
  • Yellow Fever Vaccine
  • Zoster Vaccine, Live

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bleeding problems, history of or
  • Kidney problems—Use with caution. May make these conditions worse.
  • Blood clotting problems, history of or
  • Diabetes or
  • Heart attack or stroke, recent or
  • Heart or blood vessel disease or
  • Hyperviscosity (thick blood), known or suspected or
  • Hypovolemia (low blood volume or major loss of body fluids) or
  • Paraproteinemia (paraproteins in the blood) or
  • Sepsis (serious infection in the body)—Use with caution. May cause side effects to become worse.
  • IgA (immunoglobulin A) deficiency with antibodies against IgA—Should not be used in patients with this condition.

Portions of this document last updated: Feb. 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.