Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check you at regular visits while you are using this medicine to make sure that the medicine is working properly. Blood tests may be needed to check for unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control while you are using this medicine and for 90 days after your final dose to keep from getting pregnant. Males who are taking this medicine, with female partners who can become pregnant must use effective birth control during treatment and for at least 90 days after the last dose of this medicine. If you think you have become pregnant while using the medicine, tell your doctor right away.
This can lower the number of your platelets, which are necessary for proper blood clotting. Check with your doctor immediately if you notice any unusual bleeding or bruising, black, tarry stools, or pinpoint red spots on your skin while receiving this medicine.
Cancer medicines can cause diarrhea, constipation, nausea, or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
Check with your doctor right away if you are having burning, numbness, tingling, or painful sensations in the arms, hands, legs, or feet. These could be symptoms of a condition called peripheral neuropathy.
This medicine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of face, arms, hands, lower legs, or feet, tingling of hands or feet, or unusual weight gain or loss.
If you develop a skin rash or redness or discoloration of the skin, check with your doctor as soon as possible.
Thrombotic microangiopathy (damage in the smallest blood vessels) may occur while you are using this medicine. Tell your doctor right away if you have a fever, tiredness, confusion, loss of vision, or seizures.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.
Portions of this document last updated: May 01, 2024
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