Proper Use
Drug information provided by: Merative, Micromedex®
Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.
This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Carefully follow the special meal plan your doctor gave you. This is the most important part of controlling your diabetes, and is necessary if the medicine is to work properly. Exercise regularly and test for sugar in your blood or urine as directed.
You may take this medicine with food.
Swallow the tablet whole. Do not break or cut it.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
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For oral dosage form (tablets):
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For type 2 diabetes:
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Adults:
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Patients not currently treated with metformin—At first, 50 milligrams (mg) of sitagliptin and 500 mg of metformin 2 times a day. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 100 mg of sitagliptin and 2000 mg of metformin per day.
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Patients already treated with metformin—At first, give 50 milligrams (mg) of sitagliptin 2 times a day and the same metformin dose you are already taking. For patients already taking 850 mg of metformin 2 times a day, take 50 mg of sitagliptin and 1000 mg of metformin 2 times a day. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 100 mg of sitagliptin and 2000 mg of metformin per day.
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Children—Use and dose must be determined by your doctor.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Portions of this document last updated: May 01, 2024
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