Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine should come with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food.

If you are unable to swallow the tablet whole, you may crush and mix it with 2 tablespoons of soft food or liquid. Mix and eat the mixture. If any crushed tablet pieces remain, mix it with another 2 tablespoons of soft food or liquid. Take all mixture within 1 hour of mixing. Throw away unused mixture 1 hour after mixing.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • To reduce the risk of relapse (coming back) in patients with high-risk neuroblastoma:
      • Adults and children—Dose is based on body surface area (BSA) and must be determined by your doctor. Your doctor may adjust your dose as needed and tolerated.
        • BSA of more than 1.5 meter squared (m2)—768 milligrams (mg) or 4 tablets 2 times a day.
        • BSA of 0.75 to 1.5 m2—576 mg or 3 tablets 2 times a day.
        • BSA of 0.5 to less than 0.75 m2—384 mg or 2 tablets 2 times a day.
        • BSA of 0.25 to less than 0.5 m2—192 mg or 1 tablet 2 times a day.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose and it is within 7 hours until your next regular dose, skip the missed dose and take your next dose at the regular time.

If you vomit after taking a dose, do not take an extra dose. Take the next dose at the regular time.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Portions of this document last updated: Feb. 01, 2024

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