Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. blurred vision
  3. chest pain or tightness
  4. confusion
  5. cough
  6. decreased urine
  7. difficult or labored breathing
  8. dizziness
  9. dry mouth
  10. fainting
  11. fever or chills
  12. increased thirst
  13. irregular heartbeat
  14. lightheadedness
  15. loss of appetite
  16. lower back or side pain
  17. mood changes
  18. muscle pain or cramps
  19. nausea or vomiting
  20. nervousness
  21. numbness or tingling in the hands, feet, or lips
  22. painful or difficult urination
  23. pale skin
  24. pounding in the ears
  25. rapid breathing
  26. seizures
  27. sneezing
  28. sore throat
  29. sunken eyes
  30. swelling of the hands, ankles, feet, or lower legs
  31. trouble breathing with exertion
  32. ulcers, sores, or white spots in the mouth
  33. unusual bleeding or bruising
  34. unusual tiredness or weakness
  35. wrinkled skin

Less common

  1. Change in walking and balance
  2. clumsiness or unsteadiness
  3. decreased awareness or responsiveness
  4. decreased frequency of urination
  5. headache
  6. muscle twitching or jerking
  7. pounding in the ears
  8. rhythmic movement of the muscles
  9. seeing, hearing, or feeling things that are not there
  10. severe constipation
  11. severe sleepiness
  12. shakiness in the legs, arms, hands, or feet
  13. slow or fast heartbeat
  14. stomach pain
  15. thinking abnormalities
  16. trembling or shaking of the hands or feet

Incidence not known

  1. Increased sensitivity to pain
  2. worsening of pain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Extremely shallow or slow breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Back pain
  2. diarrhea
  3. difficulty having a bowel movement (stool)
  4. difficulty with moving
  5. discouragement
  6. feeling sad or empty
  7. irritability
  8. lack or loss of strength
  9. loss of interest or pleasure
  10. muscle stiffness
  11. pain in the joints
  12. sleepiness or unusual drowsiness
  13. tiredness
  14. trouble concentrating
  15. trouble sleeping
  16. weight loss

Less common

  1. Changes in vision
  2. excessive muscle tone
  3. feeling of constant movement of self or surroundings
  4. feeling of warmth or heat
  5. flushing or redness of the skin, especially on the face and neck
  6. irritation, pain, or sores at the site of application
  7. itching skin
  8. muscle tension or tightness
  9. rash
  10. sensation of spinning
  11. sweating

Incidence not known

  1. Tooth pain
  2. trouble with gums
  3. trouble with teeth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: May 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.