Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Corticosteroids taken by mouth or injection have been shown to slow or stop growth in children and cause reduced adrenal gland function. If enough fluticasone is absorbed following inhalation, it is possible it also could cause these effects. Your doctor will want you to use the lowest possible dose of fluticasone that controls asthma. This will lessen the chance of an effect on growth or adrenal gland function. It is also important that children taking fluticasone visit their doctors regularly so that their growth rates may be monitored. Children who are taking this medicine may be more susceptible to infections, such as chickenpox or measles. Care should be taken to avoid exposure to chickenpox or measles. If the child is exposed or the disease develops, the doctor should be contacted and his or her directions should be followed carefully. Before this medicine is given to a child, you and your child's doctor should talk about the good this medicine will do as well as the risks of using it.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ArmonAir® Digihaler™ and Flovent® HFA in children 4 years of age and older as maintenance treatment for asthma. However, safety and efficacy have not been established for ArmonAir® Digihaler™ and Flovent® HFA in children younger than 4 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fluticasone in the elderly. However, elderly patients are more sensitive to the effects of Arnuity® Ellipta®, Flovent® Diskus®, or Flovent® HFA than younger adults. Elderly patients are also more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving Armonair® or Arnuity® Ellipta®. .

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Desmopressin
  • Levoketoconazole

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Adagrasib
  • Amphetamine
  • Aspirin
  • Atazanavir
  • Bemiparin
  • Boceprevir
  • Bupropion
  • Carbamazepine
  • Ceritinib
  • Clarithromycin
  • Cobicistat
  • Conivaptan
  • Cosyntropin
  • Dabrafenib
  • Darunavir
  • Dasabuvir
  • Dextroamphetamine
  • Duvelisib
  • Fedratinib
  • Fexinidazole
  • Fluconazole
  • Fosnetupitant
  • Idelalisib
  • Indinavir
  • Itraconazole
  • Ivosidenib
  • Josamycin
  • Ketoconazole
  • Larotrectinib
  • Lefamulin
  • Lenacapavir
  • Lisdexamfetamine
  • Lonafarnib
  • Lopinavir
  • Lorlatinib
  • Lumacaftor
  • Lutetium Lu 177 Dotatate
  • Macimorelin
  • Mavacamten
  • Mibefradil
  • Mifepristone
  • Nadroparin
  • Nefazodone
  • Nelfinavir
  • Netupitant
  • Nirmatrelvir
  • Olutasidenib
  • Omaveloxolone
  • Pacritinib
  • Phenobarbital
  • Pirtobrutinib
  • Posaconazole
  • Primidone
  • Ribociclib
  • Ritlecitinib
  • Ritonavir
  • Saquinavir
  • Sargramostim
  • Somatrogon-ghla
  • Telaprevir
  • Telithromycin
  • Tipranavir
  • Trofinetide
  • Troleandomycin
  • Tucatinib
  • Voriconazole

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Auranofin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Asthma attack, acute or
  • Bronchospasm (difficulty with breathing), acute or
  • Milk protein allergy, severe—Should not be used in patients with these conditions.
  • Blood vessel disease (eg, Churg-Strauss syndrome) or
  • Bone problems (eg, osteoporosis) or
  • Cataracts or
  • Glaucoma—Use with caution. May make these conditions worse.
  • Chickenpox (including recent exposure) or
  • Herpes simplex (virus) infection of the eye or
  • Infections (virus, bacteria, or fungus) or
  • Measles or
  • Tuberculosis, active or history of—Inhaled fluticasone can reduce the body's ability to fight off these infections.
  • Infection or
  • Stress or
  • Surgery or
  • Trauma—Supplementary oral corticosteroids may be needed. Check with your doctor.
  • Liver disease, moderate to severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

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Portions of this document last updated: May 01, 2024

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