Description and Brand Names
Drug information provided by: Merative, Micromedex®
US Brand Name
- Yervoy
Descriptions
Ipilimumab injection is used in combination with nivolumab to treat melanoma (a type of skin cancer) that has spread or cannot be removed by surgery. It is a monoclonal antibody that changes the immune system to help control the growth of cancer cells in the skin.
Ipilimumab injection is also used to help prevent melanoma from coming back after surgical removal.
Ipilimumab injection is used in combination with other medicines (eg, nivolumab) to treat patients with kidney cancer that has spread throughout the body.
Ipilimumab injection is used with nivolumab to treat microsatellite instability high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer (cancer of the colon or rectum) that has spread. It is given to patients who have received other cancer treatments (eg, fluoropyrimidine, oxaliplatin, irinotecan) but did not work well.
Ipilimumab injection is also used with nivolumab to treat liver cancer. It is given to patients who have previously received treatment with sorafenib.
Ipilimumab injection is also used with nivolumab as first-line treatment for metastatic (cancer that has already spread) non-small cell lung cancer (NSCLC) in patients whose tumors express PD-L1 and do not have an abnormal EGFR or ALK gene. Your doctor will perform a test to check for the PD-L1 tumor before you receive this medicine.
Ipilimumab injection is also used with nivolumab and two cycles of cancer treatment that contains platinum and another cancer medicine as first-line treatment for metastatic (cancer that has already spread) or recurrent (cancer that has come back) non-small cell lung cancer (NSCLC) in patients whose tumors do not have an abnormal EGFR or ALK gene. Your doctor will perform a test before you receive this medicine.
Ipilimumab injection is also used with nivolumab as first-line treatment for malignant pleural mesothelioma (cancer that affects the lining of the lungs and chest wall) that cannot be removed by surgery.
Ipilimumab injection is also used with nivolumab as first-line treatment for squamous cell carcinoma of the esophagus that has spread or cannot be removed by surgery.
This medicine is to be given only by or under the immediate supervision of your doctor.
This product is available in the following dosage forms:
Portions of this document last updated: Feb. 01, 2024
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