Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine exactly as directed and when symptoms of an OFF period start to return. It is important that you do not stop using your medicine unless ordered by your doctor. It is also important not to start using other medicines for your Parkinson's disease without first talking with your doctor.

This medicine should come with a patient information leaflet and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

The capsules are for inhalation only and should be used with the inhaler. Do not swallow or open the capsule.

Do not use any capsule that looks crushed, damaged, or wet.

To use the inhaler:

  • Your hands should be clean and dry when using the inhaler and capsules.
  • Remove the blue cap of the inhaler. Twist off the white mouthpiece. Load 1 capsule into the capsule chamber of the inhaler. Do not load 2 capsules at the same time. Attach the mouthpiece until you hear a click.
  • Breathe out fully and try to get as much air out of your lungs as possible. Put the mouthpiece just in front of your mouth and breathe in (inhale) deeply. If you did not hear or feel the capsule “whirl” (spin) while inhaling, you may need to take a deeper, longer breath. If you cough or stop your dose, repeat the step using the same capsule.
  • Hold your breath for about 5 to 10 seconds, then breathe out slowly.
  • Twist and pull off the mouthpiece. Remove the used capsule, then load a second capsule into the inhaler. Repeat the same steps.
  • Remove the used capsule, then load a second capsule into the inhaler and breathe in. Do not load 2 capsules at the same time.
  • You may use a dry cotton swab or tissue to clean the mouthpiece.

If you are taking multivitamin tablets or plan to start taking them, discuss this first with your doctor. Iron salts (in vitamins) may keep this medicine from working properly.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For inhalation dosage form (powder):
    • For OFF episodes in patients with Parkinson’s disease:
      • Adults—Two 42-milligram (mg) capsules (84 mg) taken as needed, for up to 5 times a day. Your doctor may adjust your dose as needed. However the dose is usually not more than 84 mg per OFF episode (not more than 1 dose or 2 capsules per OFF episode) or 420 mg per day (not more than 5 doses per day).
      • Children—Use and dose must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.

This medicine is used when symptoms of an OFF period start to return.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not store the capsules inside the inhaler.

Portions of this document last updated: Feb. 01, 2024

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