Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress at regular visits. Blood and urine tests may be needed to check for unwanted effects. Your doctor will do tests before starting treatment, every month for 12 months, and then every 3 months during treatment with this medicine.

Do not use this medicine together with aliskiren (Tekturna®) or other blood pressure medicine (eg, angiotensin receptor blocker, endothelin receptor blocker).

Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, your doctor will do tests before starting, during treatment, and 1 month after stopping this medicine to make sure you are not pregnant. Use an effective form of birth control before starting, during treatment, and for 1 month after your final dose to keep from getting pregnant. Ask your doctor which form of birth control is right for you. If you think you have become pregnant while using the medicine, tell your doctor right away.

This medicine may cause serious liver problems. Check with your doctor right away if you have dark urine, fatigue, loss of appetite, nausea or vomiting, severe stomach pain, or yellow eyes or skin.

Check with your doctor right away if you have blurred vision, confusion, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, sweating, or unusual tiredness or weakness. These may be symptoms of hypotension (low blood pressure).

This medicine may cause serious kidney problems. Check with your doctor right away if you have agitation, coma, confusion, decreased urine output, depression, dizziness, headache, hostility, irritability, lethargy, muscle twitching, nausea, rapid weight gain, seizures, stupor, swelling of the face, ankles, or hands, or unusual tiredness or weakness.

Check with your doctor right away if you have confusion, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, stomach pain, trouble breathing, or weakness or heaviness of the legs. These may be symptoms of hyperkalemia (high potassium in the blood).

This medicine may cause fluid retention (too much water in the body). Check with your doctor right away if you have decrease in amount of urine, noisy, rattling, or trouble breathing, swelling of the face, hands, feet, or lower legs, or weight gain.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.