Proper Use

Drug information provided by: Merative, Micromedex®

COVID-19: A doctor or other trained health professional will give you this medicine. It is given as a shot under your skin for 10 days.

Rheumatoid arthritis, NOMID, and DIRA: This medicine is given as a shot under your skin. Anakinra may sometimes be given at home to patients who do not need to be in the hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use the medicine.

This medicine comes with a Patient Information, Instructions for Use leaflet, and Fact Sheet for Patients and Caregivers. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself or your child a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems.

Use a new needle, unopened prefilled syringe, or syringe each time you inject your medicine.

You might not use all of the medicine in each prefilled syringe. Use each syringe only one time. Do not save an open syringe. If the medicine in the syringe has changed color, or if you see particles in it, do not use it.

Use the medicine at the same time each day.

Throw the used needles away in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (solution):
    • For rheumatoid arthritis:
      • Adults—100 milligrams (mg) per day injected under the skin.
      • Children—Use is not recommended.
    • For neonatal-onset multisystem inflammatory disease (NOMID) and deficiency interleukin-1 receptor antagonist (DIRA):
      • Adults and children—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 1 to 2 milligrams (mg) per kilogram (kg) of body weight injected under the skin per day. Your doctor may increase your dose as needed. However, the dose is usually not more than 8 mg per kg of body weight per day.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Do not shake the medicine. Protect it from light.

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Portions of this document last updated: April 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.