Before Using

Drug information provided by: Merative, Micromedex®

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Children may be especially sensitive to the effects of dental anesthetics. This may increase the chance of unwanted effects, some of which can be serious, during treatment. When using a dental anesthetic for a child, be very careful not to use more of the medicine than directed on the label, unless otherwise directed by your health care professional. Teething medicines that contain benzocaine may be used in babies 4 months of age and older. One product that contains benzocaine (Orabase-B with Benzocaine) may be used in children 6 years of age and older. Most of the other nonprescription (over-the-counter [OTC]) medicines that contain a dental anesthetic may be used in children 2 years of age and older. However, these other nonprescription products should not be used in infants or children younger than 2 years of age unless prescribed by a health care professional.

Geriatric

Elderly people are especially sensitive to the effects of many local anesthetics. This may increase the chance of side effects during treatment, especially with lidocaine. Nonprescription (over-the-counter [OTC]) products containing local anesthetics are not likely to cause problems. However, elderly people should be especially careful not to use more medicine than directed on the package label, unless otherwise directed by a medical doctor or a dentist.

Pregnancy

Dental anesthetics have not been reported to cause birth defects or other problems in humans.

Breastfeeding

Dental anesthetics have not been reported to cause problems in nursing babies.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

  • Dronedarone
  • Saquinavir
  • Vernakalant

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acecainide
  • Alcuronium
  • Amifampridine
  • Amiodarone
  • Amprenavir
  • Arbutamine
  • Articaine
  • Atracurium
  • Benoxinate
  • Benzocaine
  • Benzyl Alcohol
  • Bretylium
  • Bupivacaine Liposome
  • Bupropion
  • Chloroprocaine
  • Cisatracurium
  • Cobicistat
  • Cocaine
  • Darunavir
  • Dasabuvir
  • Delavirdine
  • Dibucaine
  • Disopyramide
  • Dofetilide
  • Donepezil
  • Doxacurium
  • Dronedarone
  • Dyclonine
  • Encainide
  • Ethyl Chloride
  • Etidocaine
  • Etravirine
  • Fazadinium
  • Flecainide
  • Fosamprenavir
  • Fosphenytoin
  • Gallamine
  • Hexafluorenium
  • Hyaluronidase
  • Ibutilide
  • Levobupivacaine
  • Lidocaine
  • Lopinavir
  • Mepivacaine
  • Metocurine
  • Metoprolol
  • Mexiletine
  • Mivacurium
  • Moricizine
  • Nadolol
  • Opicapone
  • Pancuronium
  • Phenytoin
  • Pipecuronium
  • Pramoxine
  • Prilocaine
  • Procainamide
  • Procaine
  • Propafenone
  • Proparacaine
  • Quinidine
  • Rapacuronium
  • Rocuronium
  • Ropivacaine
  • Sotalol
  • St John's Wort
  • Succinylcholine
  • Telaprevir
  • Tetracaine
  • Tocainide
  • Tubocurarine
  • Vecuronium

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Portions of this document last updated: April 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.