Description and Brand Names
Drug information provided by: Merative, Micromedex®
US Brand Name
- Enhertu
Descriptions
Fam-trastuzumab deruxtecan-nxki injection is used to treat HER2-positive (IHC 3+ or ISH positive) metastatic (cancer that has spread to other parts of the body) or unresectable (cancer that cannot be removed with surgery) breast cancer in patients who have previously received an anti-HER2 breast cancer treatment for metastatic disease or have breast cancer that has come back during or within 6 months of completing treatment for early-stage breast cancer.
Fam-trastuzumab deruxtecan-nxki injection is also used to treat HER2-low metastatic (cancer that has spread to other parts of the body) or unresectable (cancer that cannot be removed with surgery) breast cancer in patients who have previously received treatment for metastatic disease or have breast cancer that has come back during or within 6 months of completing treatment (after surgery).
Fam-trastuzumab deruxtecan-nxki injection is also used to treat metastatic (cancer that has spread to other parts of the body) or unresectable (cancer that cannot be removed with surgery) non-small cell lung cancer (NSCLC) in patients whose cancer has an abnormal HER2 gene and who have previously received treatment.
Fam-trastuzumab deruxtecan-nxki injection is also used to treat HER2-positive (IHC 3+ or IHC 2+/ ISH positive) metastatic (cancer that has spread to other parts of the body) or locally advanced (cancer that has spread to areas near the stomach) stomach cancer called gastric or gastroesophageal junction (GEJ) adenocarcinoma in patients who have previously received trastuzumab-based regimen.
Fam-trastuzumab deruxtecan-nxki injection is also used to treat HER2-positive (IHC 3+) metastatic (cancer that has spread to other parts of the body) or unresectable (cancer that cannot be removed with surgery) solid tumors in patients who have previously received treatment that did not work well.
Your doctor will test for the presence of the HER2 gene. HER2 protein is produced by some tumors. Fam-trastuzumab deruxtecan-nxki interferes with the growth of this protein which also prevents tumor growth. The tumor cells will then be destroyed by the body.
This medicine is to be given only by or under the immediate supervision of your doctor.
This product is available in the following dosage forms:
Portions of this document last updated: May 01, 2024
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