Proper Use
Drug information provided by: Merative, Micromedex®
Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.
This medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.
Take this medicine with fat-containing foods, including butter, cheese pizza, eggs, peanut butter, or whole milk dairy products (eg, whole milk, cheese, yogurt, breast milk, or infant formula).
Swallow the tablet whole.
To use the oral granules:
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Shake the packet gently before opening it.
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Open one packet and pour the contents into 1 teaspoon (5 milliliters) of room temperature or cold soft food or liquid (eg, applesauce, pureed fruits or vegetables, yogurt, water, breast milk, infant formula, milk, or juice).
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Mix the granules with the soft food or liquid.
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After mixing, give this medicine to your child within 1 hour. Make sure all medicine is taken.
Do not eat grapefruit or Seville oranges or drink grapefruit juice or Seville orange juice while you are using this medicine. These may cause the amount of medicine absorbed in the blood to be too high.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
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For oral dosage forms (granules, tablets):
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For cystic fibrosis:
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Adults and children 6 years of age and older—150 milligrams (mg) every 12 hours.
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Children 6 months to younger than 6 years of age—Dose is based on your body weight and must be determined by your doctor.
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Weighing 14 kilograms (kg) or more—The dose is usually one 75 milligrams (mg) packet every 12 hours.
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Weighing 7 kg to less than 14 kg—The dose is usually one 50 mg packet every 12 hours.
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Weighing 5 kg to less than 7 kg—The dose is usually one 25 mg packet every 12 hours.
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Children 4 months to younger than 6 months of age weighing 5 kg or more—Dose is based on your body weight and must be determined by your doctor. The dose is usually one 25 mg packet every 12 hours.
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Children 2 months to younger than 4 months of age weighing 3 kg or more—Dose is based on your body weight and must be determined by your doctor. The dose is usually one 13.4 mg packet every 12 hours.
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Children 1 month to younger than 2 months of age weighing 3 kg or more—Dose is based on your body weight and must be determined by your doctor. The dose is usually one 5.8 mg packet every 12 hours.
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Children younger than 1 month of age—Use is not recommended.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
If you miss a dose and it is 6 hours or less from your regular schedule, take it as soon as you can. If you miss a dose and it is more than 6 hours away from your next regular dose, skip the missed dose and go back to your regular schedule.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Portions of this document last updated: May 01, 2024
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