Precautions
Drug information provided by: Merative, Micromedex®
The effects of the opioid medicine may last longer than the effects of the nalmefene. This means the breathing problems and sleepiness could come back. Always call for emergency help after the first dose of nalmefene.
Severe opioid withdrawal symptoms may happen suddenly after receiving this medicine. These include body aches, a fever, sweating, runny nose, sneezing, goose bumps, yawning, weakness, shivering or trembling, nervousness, restlessness or irritability, diarrhea, nausea or vomiting, stomach cramps, fast heartbeat, and increased blood pressure.
Some types of opioid medications (eg, buprenorphine, pentazocine) may require larger or repeat doses of nalmefene to reverse the opioid effects.
Portions of this document last updated: Feb. 01, 2024
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